John Odigie Oyegun (born 12 August 1939) is a Nigerian politician who served as the first national chairman of All Progressives Congress (APC) in Nigeria. He was also the Executive Governor of Edo State between 1992 and 1993, during the aborted Nigerian Third Republic.

Oyegun led then opposition APC and Muhammad Buhari to victory in 2015 after defeating ruling People’s Democratic Party, PDP and President Goodluck Jonathan. It was the first time an incumbent president and a ruling party was defeated in a presidential poll in Nigeria.